IGF-1 LR3 1mg Research Peptide
IGF-1 LR3 (Long R3 IGF-1) is an 83–amino acid analogue of insulin-like growth factor-1. It has an arginine substitution at position 3 and a 13–amino acid N-terminal extension, which reduce binding to IGF binding proteins. It is supplied as a 1mg lyophilized vial.
Research Applications
IGF-1 LR3 is widely used as a cell culture supplement and as a research tool for IGF-1 receptor signaling, including PI3K/Akt and MAPK pathways, cell proliferation, and protein synthesis in muscle and other cell models.
Why Researchers Choose It
- Standard reagent for IGF-1 receptor research
- Reduced IGFBP binding for consistent in-vitro activity
- Lyophilized for stability in storage and transit
- Batch-tracked with third-party COA testing
Product Specifications
| Product | IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) |
| Length | 83 amino acids |
| CAS Number | 946870-92-4 |
| Molecular Weight | ≈ 9,111 Da |
| Form | Lyophilized (freeze-dried) powder |
| Size | 1mg |
| Purity | Verified per batch (see COA) |
Storage & Handling
- Store the sealed vial at -20°C for long-term stability; 2–8°C is suitable for short-term storage.
- Protect from moisture, heat, and direct light. Let the vial reach room temperature before opening to limit condensation.
- Handle in a clean, controlled laboratory environment using appropriate PPE.
Frequently Asked Questions
What does LR3 mean?
Long R3 refers to the 13–amino acid N-terminal extension (Long) and the arginine substitution at position 3 (R3).
Why is IGF-1 LR3 used in cell culture?
Its low affinity for IGF binding proteins keeps it more consistently active in culture media than native IGF-1.
Does this product come with a Certificate of Analysis?
Yes. Every batch is supported by independent third-party analytical testing confirming identity and purity.
What does lyophilized mean?
Lyophilized means freeze-dried. Removing water this way gives the peptide a stable powder form that holds up well in storage and shipping.
Is this product approved for human or animal use?
No. It is sold strictly for in-vitro laboratory research.
Research Use Only Disclaimer
This product is supplied strictly for in-vitro laboratory research and analytical use. It is not intended for human or animal consumption, is not a drug, food, or cosmetic, and has not been evaluated or approved by the FDA. No instructions for preparation, administration, or dosage are provided. Purchasers must be 21 or older and are solely responsible for the lawful handling, storage, and use of this material.















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